Depression linked to telomere enzyme, aging, chronic disease

Depression linked to telomere enzyme, aging, chronic disease

Now a research team led by Owen Wolkowitz, MD, professor of psychiatry at UC San Francisco, has found that within cells of the immune system, activity of an enzyme called telomerase is greater, on average, in untreated individuals with major depression. The preliminary findings from his latest, ongoing study will be reported today at the annual meeting of the American Psychiatric Association in San Francisco.

Telomerase is an enzyme that lengthens protective end caps on the chromosomes' DNA, called telomeres. Shortened telomeres have been associated with earlier death and with chronic diseases in population studies.

The heightened telomerase activity in untreated major depression might represent the body's attempt to fight back against the progression of disease, in order to prevent biological damage in long-depressed individuals, Wolkowitz said.

The researchers made another discovery that may suggest a protective role for telomerase. Using magnetic resonance imaging (MRI), they found that, in untreated, depressed study participants, the size of the hippocampus, a brain structure that is critical for learning and memory, was associated with the amount of telomerase activity measured in the white blood cells. Such an association at a single point in time cannot be used to conclude that there is a cause-and-effect relationship with telomerase helping to protect the hippocampus, but it is plausible, Wolkowitz said.

Remarkably, the researchers also found that the enzyme's activity went up when some patients began taking an antidepressant. In fact, depressed participants with lower telomerase activity at baseline -- as well as those in whom enzyme activity increased the most with treatment -- were the most likely to become less depressed with treatment.

"Our results are consistent with the beneficial effect of telomerase when it is boosted in animal studies, where it has been associated with the growth of new nerve cells in the hippocampus and with antidepressant-like effects, evidenced by increased exploratory behavior," Wolkowitz said. Wolkowitz cautions that his new findings are preliminary due to the small size of the study and must be confirmed through further research.

The researchers also measured telomere length in the same immune cells. Only very chronically depressed individuals showed telomere shortening, Wolkowitz said.

"The longer people had been depressed, the shorter their telomeres were," he said. "Shortened telomere length has been previously demonstrated in major depression in most, but not all, studies that have examined it. The duration of depression may be a critical factor."

The 20 depressed participants enrolled in the study had been untreated for at least six weeks and had an average lifetime duration of depression of about 13 years. After baseline evaluation and laboratory measures, 16 of the depressed participants were treated with sertraline, a member of the most popular class of anti-depressants, the serotonin-selective-reuptake-inhibitors (SSRIs), and then evaluated again after eight weeks. There were 20 healthy participants who served as controls.

The ongoing study still is accepting depressed participants who are not now taking antidepressants. Wolkowitz's team also studies chronic inflammation and the biochemical phenomenon of oxidative stress, which he said have often been reported in major depression. Wolkowitz is exploring the hypothesis that inflammation and oxidative stress play a role in telomere shortening and accelerated aging in depression.

"New insights into the mechanisms of these processes may well lead to new treatments -- both pharmacological and behavioral -- that will be distinctly different from the current generation of drugs prescribed to treat depression," he said. "Additional studies might lead to simple blood tests that can measure accelerated immune-cell aging."

Wolkowitz's research is funded by the National Institutes of Health. He is on the scientific advisory board of Telome Health, Inc., a private biotechnology company.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

Electronic Components distributor:http://www.suvsystem.com

Connectors Distributor:http://www.suvsystem.com/l/Connectors-1.html

IC Distributor:http://www.suvsystem.com/l/IC(Integrated-Circuits)-1.html

LED Distributor:http://www.suvsystem.com/l/LED-1.html

Capacitor Distributor:http://www.suvsystem.com/l/Capacitor-1.html

Transistor Distributor:http://www.suvsystem.com/l/Transistors-1.html

Resistor Distributor:http://www.suvsystem.com/l/Resistors-1.html

Diode Distributor:http://www.suvsystem.com/l/Diodes-1.html

SUV System Ltd insists on the managing faith ofsincereness,speciality,foresight, win-win,so we build up stable-relationship customers located all over the world, including the States, Europe, Argentina, UAE, Malaysia, Australia,and India etc

we are focus on the following fields,and hope we can help you.

CRGV2010F287K CRGV2010F280K CRGV2010F274K CRGV2010F267K CRGV2010F261K CRGV2010F255K CRGV2010F249K CRGV2010F243K CRGV2010F237K CRGV2010F232K CRGV2010F226K CRGV2010F221K CRGV2010F215K CRGV2010F210K CRGV2010F205K CRGV2010F200K CRGV2010F1M96 CRGV2010F1M91 CRGV2010F1M87 CRGV2010F1M82 CRGV2010F1M78 CRGV2010F1M74 CRGV2010F1M69 CRGV2010F1M65 CRGV2010F1M62 CRGV2010F1M58 CRGV2010F1M54 CRGV2010F1M5 CRGV2010F1M47 CRGV2010F1M43 CRGV2010F1M4 CRGV2010F1M37 CRGV2010F1M33 CRGV2010F1M3 CRGV2010F1M27 CRGV2010F1M24 CRGV2010F1M21 CRGV2010F1M18 CRGV2010F3M48 CRGV2010F3M4
http://www.suvsystem.com/a/1432.aspx

Vast methane-based ecosystem uncovered

Vast methane-based ecosystem uncovered

The seep lies deep in the western North Atlantic Ocean, far from the life-sustaining energy of the sun. Mussels blanketing the the seep rely on bacteria that use the methane to make energy. The process, known as chemosynthesis, forms the basis for life in the harsh environment and could help scientists better understand how organisms can survive under these types of extreme conditions.

"UNCW and FSU have done two previous cruises together and this is perhaps our biggest discovery," said UNCW researcher Dr. Steve Ross. "Studies of this kind and of these communities help scientists understand how life thrives in harsh environments, and perhaps even on other planets."

The new seep discovery is only the third documented seep site on the U.S. Atlantic Coast, and by far the most extensive; the two seep areas at this site are estimated to be at least a kilometer long and in places hundreds of meters across. Sea cucumbers were also seen tucked into the tight mounds of mussels and shrimp swam above them. Many species of fishes, including some with unusual behaviors, were also common around the unique ecosystem..

Stationed aboard NOAA's Ronald H. Brown research vessel, the research teams used the diverse capabilities of the Woods Hole Oceanographic Institution's Remotely Operated Vehicle (ROV), Jason II, to document and study the newly discovered methane seep.. The teams have been able to capture high definition video, sample the sediment at the site, collect live mussels for genetic and reproductive studies, collect large dead shells and rocks for aging analysis, take water samples to examine water chemistry, and sample associated animals to examine food webs.

The seep discovery could potentially play an important role in advancing scientific understanding of hydrocarbon resources and gas hydrates (important possible future energy resources) along the US continental slope .

Major funding for the research expedition was provided by the Bureau of Ocean Energy Management, with NOAA providing funding for the Ronald H. Brown and Jason ROV. US Geological Survey and other collaborators also provided a variety of resources.

TAG:Extreme Survival Fish Marine Biology Sustainability Energy and the Environment Renewable Energy

First genomic survey of human skin fungal diversity

First genomic survey of human skin fungal diversity

Human skin surfaces are complex ecosystems for microorganisms, including fungi, bacteria and viruses, which are known collectively as the skin microbiome. Although fungal infections of the skin affect about 29 million people in the United States, fungi can be slow and hard to grow in laboratories, complicating diagnosis and treatment of even the most common fungal skin conditions, such as toenail infections.

The research team from the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying fungi. The study appears in the May 22, 2013 early online issue of Nature.

The researchers found that a single type of fungus, belonging to the genus Malassezia, is predominant on the head and trunk. Hands, which harbor a great diversity of bacteria, are home for relatively few types of fungi. In contrast, feet, including toenails, heels and toe webs contain tremendous diversity.

"Applying DNA sequencing to a study of the skin's fungi is the natural progression in understanding microbial life that co-exists on our bodies," said NHGRI Scientific Director Daniel Kastner, M.D., Ph.D. "Along with recent genome sequencing to define bacterial diversity, this analysis of fungal diversity provides a more complete human microbiome picture."

"Fungal communities occupy complex niches, even on the human body," said Heidi Kong, M.D., co-senior author and an investigator in the dermatology branch of NCI's Center for Cancer Research. "By gaining a more complete awareness of the fungal and bacterial ecosystems, we can better address associated skin diseases, including skin conditions which can be related to cancer treatments."

The researchers collected samples at 14 body sites from 10 healthy adults. DNA sequencing of the fungi in the samples identified fragments of DNA, called phylogenetic markers, which can be counted and used to distinguish one type of fungus from another. The sequencing efforts generated more than 5 million markers, from the samples, representing more than 80 fungal types, or genera. In contrast, traditional culturing methods produced 130 colonies of fungi that represented only 18 fungal genera.

In 20 percent of the study participants, the researchers observed problems such as heel and toe web scaling or toenail changes consistent with possible fungal infections. From genome sequencing analysis, the researchers found that different individuals with heel site infections have common fungal communities at that site, while those with toenail infections display tremendously different fungal communities.

"DNA sequencing reveals the great diversity of fungi, even those that are hard to grow in culture," said Julie Segre, Ph.D., co-senior author and senior investigator, NHGRI Genetics and Molecular Biology Branch. Her expertise is the development of microbial DNA sequencing technology. "DNA sequencing enabled us to learn immeasurably more about where fungi predominate as a part of the human skin microbiome."

The researchers identified fungi from two phyla, Ascomycetes and Basidiomycetes, as part of the normal fungal census at the 14 skin sites. The most common genus Malassezia was present in 11 of 14 sites sampled on the body. The researchers found Malassezia fungus on every skin surface of healthy volunteers, whether on the back of the head, behind the ears, in nostrils and on the heels. Heels were also home to many additional fungi, including the genera Aspergillus, Cryptococcus, Rhodotorula, and Epicoccum.

"DNA sequence-based methods of identification enabled us to differentiate among species of fungi and to conclude that the diversity of fungi is highly dependent on the body site rather than the person who is sampled," said Dr. Kong. A dermatologist, Dr. Kong explained why these sites were selected for exploration: "Our study focused on areas of the skin where we commonly find skin diseases that have been associated with fungi."

The most complex site, the heel, is home to about 80 genus-level types of fungi. The researchers found about 60 types in toenail swab samples and 40 types in samples from the webs of the toes. Sites with moderate fungal diversity are inside the bend of the arm, inside of the forearm and palm, with each location supporting 18 to 32 genera of fungi. Surprisingly, head and trunk body sites -- including the back, back of the neck, inside the ears, behind the ears, and between the eyebrows -- have far fewer fungi types, with just two to 10 genera each.

The research team compared fungal diversity data with the skin bacteria on the same healthy adults. They found that while arms have high measures of bacterial diversity, they have lower fungal diversity. They found the reverse to be true for sites on the feet. Core body sites had neither a high bacterial diversity nor a high fungal diversity. The researchers had previously shown that bacterial diversity can be predicted by whether skin is moist, dry or oily. Fungal diversity, instead, seems to depend upon where a particular skin site is on the body.

The researchers observed, in addition, that there is greater similarity in the fungal community structure on the left and right sides of the same person's body compared to the same body parts on any two individuals. Fungal communities also appear to be quite stable over time, with little change when tested on two separate occasions, up to three months apart.

"The data from our study gives us a baseline about normal individuals that we never had before," Dr. Segre said. "The bottom line is your feet are teeming with fungal diversity, so wear your flip flops in locker rooms if you don't want to mix your foot fungi with someone else's fungi."

TAG:Skin Care Human Biology Psoriasis Fungus Microbes and More Microbiology

Largest genetic sequencing study of human disease

Largest genetic sequencing study of human disease

May 22, 2013 — Researchers from Queen Mary, University of London have led the largest sequencing study of human disease to date, investigating the genetic basis of six autoimmune diseases.

The exact cause of these diseases -- autoimmune thyroid disease, celiac disease, Crohn's disease, psoriasis, multiple sclerosis and type 1 diabetes- is unknown, but is believed to be a complex combination of genetic and environmental factors. In each disease only a proportion of the heritability is explained by the identified genetic variants. The techniques used to date, have generally identified common (in the population) variants of weak effect.

In this study, using high-throughput sequencing techniques,a global team of scientists sought to identify new variants, including rare and potentially high risk ones, in 25 previously identified risk genes in a sample of nearly 42,000 individuals (24,892 with autoimmune disease and 17,019 controls).

It has been suggested -- in the 'rare-variant synthetic genome-wide association hypothesis' -- that a small number of rare variants in risk genes are likely to be a major cause of the heritability of these conditions. However, the study published today in the journal Nature, suggests that the genetic risk of these diseases more likely involves a complex combination of hundreds of weak-effect variants which are each common in the population.

The authors estimate that rare variants in these risk genes account for only around three per cent of the heritability of these conditions that can be explained by common variants.

David van Heel, Professor of Gastrointestinal Genetics at Barts and The London School of Medicine and Dentistry at Queen Mary and director of the Barts and The London Genome Centre, led the study. He said: "These results suggests that risk for these autoimmune diseases is not due to a few high-risk genetic variations but seems rather due to a random selection from many common genetic variants which each have a weak effect.

"For each disease there are probably hundreds such variants and the genetic risk is likely to come from inheriting a large number of these variants from both parents. If this is the case then it may never be possible to accurately predict an individual's genetic risk of these common autoimmune diseases. However, the results do provide important information about the biological basis of these conditions and the pathways involved, which could lead to the identification new drug targets."

The research utilised high-throughput sequencing techniques performed at the Barts and The London Genome Centre and demonstrated for the first time that the sequencing can call genotypes as accurately as 'gold standard techniques' such as genotyping array platforms. Additional laboratory work was carried out at the Blizard institute at Queen Mary.

Professor Richard Trembath, Vice Principal and Executive Dean for Health at Barts and The London School of Medicine and Dentistry, Queen Mary, and a co-author on the paper said: "The results prompt a re-assessment of the genetic architecture that determines risk for development of common auto-immune disorders and will fuel future careful assessment of regions of the human genome beyond those presently known to confer susceptibility to these important medical conditions."

This study was primarily funded by the Medical Research Council with additional funding from Coeliac UK.

TAG:Personalized Medicine Diseases and Conditions Asthma Genes Cholesterol Chronic Illness

Model of Sun's magnetic field created

Model of Sun's magnetic field created

Scientists have known since the 18th Century that the Sun regularly oscillates between periods of high and low solar activity in an 11-year cycle, but have been unable to fully explain how this cycle is generated.

In the 'Information Age', it has become increasingly important to be able to understand the Sun's magnetic activity, as it is the changes in its magnetic field that are responsible for 'space weather' phenomena, including solar flares and coronal mass ejections. When this weather heads in the direction of Earth it can damage satellites, endanger astronauts on the International Space Station and cause power grid outages on the ground.

The research, published in the journal Nature, explains how the cyclical nature of these large-scale magnetic fields emerges, providing a solution to the mathematical equations governing fluids and electromagnetism for a large astrophysical body.

The mechanism, known as a dynamo, builds on a solution to a reduced set of equations first proposed in the 1950s which could explain the regular oscillation but which appeared to break down when applied to objects with high electrical conductivity. The mechanism takes into account the 'shear' effect of mass movement of the ionised gas, known as plasma, which makes up the Sun. More importantly it does so in the extreme parameter regime that is relevant to astrophysical bodies.

"Previously, dynamos for large, highly conducting bodies such as the Sun would be overwhelmed by small-scale fluctuations in the magnetic field. Here, we have demonstrated a new mechanism involving a shear flow, which served to damp these small-scale variations, revealing the dominant large-scale pattern," said Professor Steve Tobias, from the University of Leeds' School of Mathematics, a co-author of the research.

What is more, this mechanism could be used to describe other large, spinning astronomical bodies with large-scale magnetic fields such as galaxies.

The dynamo was developed through simulations using the high-performance computing facilities located at the University of Leeds.

"The fact that it took 50 years and huge supercomputers shows how complicated the dynamo process really is." said Prof Fausto Cattaneo, from the University of Chicago's Department of Astronomy and Astrophysics.

The presence of spots on the Sun has been known since antiquity, and further analysed after the invention of the telescope by Galileo in the 16th Century. However, their cyclic nature, with periods of high activity (lots of sunspots) and low activity (few sunspots) following each other, was not identified until the 18th Century. At the start of the 20th Century it was then recognised that these sunspots were the result of the Sun's magnetic field. Since then much effort has been devoted to understanding what processes lead to the formation of sunspots and the origin of their cyclic behaviour.

TAG:Sun Solar Flare Astronomy Space Telescopes Space Exploration Northern Lights

Fragile mega-galaxy is missing link in history of cosmos

Fragile mega-galaxy is missing link in history of cosmos

May 22, 2013 — Two hungry young galaxies that collided 11 billion years ago are rapidly forming a massive galaxy about 10 times the size of the Milky Way, according to UC Irvine-led research published Wednesday in the journal Nature.

Capturing the creation of this type of large, short-lived star body is extremely rare -- the equivalent of discovering a missing link between winged dinosaurs and early birds, said the scientists, who relied on the once-powerful Herschel space telescope and observatories around the world. The new mega-galaxy, dubbed HXMM01, "is the brightest, most luminous and most gas-rich submillimeter-bright galaxy merger known," the authors write.

HXMM01 is fading away as fast as it forms, a victim of its own cataclysmic birth. As the two parent galaxies smashed together, they gobbled up huge amounts of hydrogen, emptying that corner of the universe of the star-making gas.

"These galaxies entered a feeding frenzy that would quickly exhaust the food supply in the following hundreds of million years and lead to the new galaxy's slow starvation for the rest of its life," said lead author Hai Fu, a UC Irvine postdoctoral scholar.

The discovery solves a riddle in understanding how giant elliptical galaxies developed quickly in the early universe and why they stopped producing stars soon after. Other astronomers have theorized that giant black holes in the heart of the galaxies blew strong winds that expelled the gas. But cosmologist Asantha Cooray, the UC Irvine team's leader, said that they and colleagues across the globe found definitive proof that cosmic mergers and the resulting highly efficient consumption of gas for stars are causing the quick burnout.

"Finding this type of galaxy is as important as the discovery of the archaeopteryx was in understanding dinosaurs' evolution into birds, because they were both caught at a critical transitional phase," Fu said.

The new galaxy was initially spotted by UC Irvine postdoctoral scholar Julie Wardlow, also with Cooray's group. She noticed "an amazing, bright blob" in images of the so-called cold cosmos -- areas where gas and dust come together to form stars -- recorded by the European Space Agency's Herschel telescope with important contributions from NASA's Jet Propulsion Laboratory in Pasadena. "Herschel captured carpets of galaxies, and this one really stood out."

Follow-up views at a variety of wavelengths were obtained at more than a dozen ground-based observatories, particularly the W. M. Keck Observatory in Hawaii.

TAG:Galaxies Astrophysics Stars Cosmology Astronomy Space Telescopes

Promising new approach to treatment of lung cancer

Promising new approach to treatment of lung cancer

This advance in nanomedicine combines the extraordinarily small size of nanoparticles, existing cancer drugs, and small interfering RNA (siRNA) that shut down the ability of cancer cells to resist attack.

The combination of these forces resulted in the virtual disappearance of lung tumors in experimental animals.

Lung cancer is the leading cancer killer in both men and women. Despite advances in surgery, chemotherapy still plays a major role in its treatment. However, that treatment is constrained by the toxic effects of some drugs needed to combat it and the difficulty of actually getting those drugs into the lungs.

The findings were made by Oleh Taratula at Oregon State University and Tamara Minko and O. Garbuzenko at Rutgers University and the Cancer Institute of New Jersey. They were just published in the Journal of Controlled Release.

"Lung cancer damage is usually not localized, which makes chemotherapy an important part of treatment," said Taratula, an assistant professor in the OSU College of Pharmacy and co-author on this study. "However, the drugs used are toxic and can cause organ damage and severe side effects if given conventionally through intravenous administration.

"A drug delivery system that can be inhaled is a much more efficient approach, targeting just the cancer cells as much as possible," he said. "Other chemotherapeutic approaches only tend to suppress tumors, but this system appears to eliminate it."

A patent is being applied for on the technology, and more testing will be necessary before it is ready for human clinical trials, the researchers said.

The foundation of the new system is a "nanostructured lipid nanocarrier," tiny particles much smaller than a speck of dust that are easily inhaled and also readily attach to cancer cells. This carrier system delivers the anticancer drug. However, it also brings siRNA that makes the cancer cell more vulnerable.

Cancer cells often have two forms of resistance to drugs -- "pump" resistance that tends to pump the drug out of cells, and "nonpump" resistance that helps keep the cell from dying. The siRNA used in this system helps to eliminate both those forms of resistance, and leaves the cancer cell vulnerable to the drug being used to kill it.

By being inhaled, this system also avoids degradation of the chemotherapeutic agents that occurs when they are injected, researchers said. They arrive in more intact form, ready to do their job on lung cancer cells, while minimizing any side effects.

In more conventional chemotherapy for lung cancer, the drugs tend to accumulate in the liver, kidney and spleen, with much less of the drugs ever making it to the lungs. In this study, the amount of the drug delivered to the lungs rose to 83 percent with the inhalation approach, versus 23 percent with injection.

This work was supported by the National Cancer Institute, National Science Foundation, and the Department of Defense.

TAG:Lung Cancer Colon Cancer Cancer Prostate Cancer Lung Disease Diseases and Conditions

Footwear's (carbon) footprint: Bulk of shoes' carbon footprint comes from manufacturing processes

Footwear's (carbon) footprint: Bulk of shoes' carbon footprint comes from manufacturing processes

But what's surprising to researchers isn't the size of a shoe's carbon footprint, but where the majority of that footprint comes from.

The researchers found that more than two-thirds of a running shoe's carbon impact can come from manufacturing processes, with a smaller percentage arising from acquiring or extracting raw materials. This breakdown is expected for more complex products such as electronics, where the energy that goes into manufacturing fine, integrated circuits can outweigh the energy expended in processing raw materials. But for "less-advanced" products -- particularly those that don't require electronic components -- the opposite is often the case.

So why does a pair of sneakers, which may seem like a relatively simple product, emit so much more carbon dioxide in its manufacturing phase?

A team led by Randolph Kirchain, principal research scientist in MIT's Materials Systems Laboratory, and research scientist Elsa Olivetti broke down the various steps involved in both materials extraction and manufacturing of one pair of running shoes to identify hotspots of greenhouse-gas emissions. The group found that much of the carbon impact came from powering manufacturing plants: A significant portion of the world's shoe manufacturers are located in China, where coal is the dominant source of electricity. Coal is also typically used to generate steam or run other processes in the plant itself.

A typical pair of running shoes comprises 65 discrete parts requiring more than 360 processing steps to assemble, from sewing and cutting to injection molding, foaming and heating. Olivetti, Kirchain and their colleagues found that for these small, light components such processes are energy-intensive -- and therefore, carbon-intensive -- compared with the energy that goes into making shoe materials, such as polyester and polyurethane.

The group's results, Kirchain says, will help shoe designers identify ways to improve designs and reduce shoes' carbon footprint. He adds that the findings may also help industries assess the carbon impact of similar consumer products more efficiently.

"Understanding environmental footprint is resource intensive. The key is, you need to put your analytical effort into the areas that matter," Kirchain says. "In general, we found that if you have a product that has a relatively high number of parts and process steps, and that is relatively light [weight], then you want to make sure you don't overlook manufacturing."

Kirchain and his colleagues have published their results in the Journal of Cleaner Production.

The sum of a shoe's parts

In 2010, nearly 25 billion shoes were purchased around the world, the majority of them manufactured in China and other developing countries. As Kirchain and his co-authors write in their paper, "An industry of that scale and geographic footprint has come under great pressure regarding its social and environmental impact."

In response, companies have started to take account of their products' greenhouse-gas contributions, in part by measuring the amount of carbon dioxide associated with every process throughout a product's lifecycle. One such company, ASICS, an athletic equipment company based in Japan, approached Kirchain to perform a lifecycle assessment for a running shoe manufactured in China.

The team took a "cradle-to-grave" approach, breaking down every possible greenhouse gas-emitting step: from the point at which the shoes' raw materials are extracted to the shoes' demise, whether burned, landfilled or recycled.

The researchers divided the shoes' lifecycle into five major stages: materials, manufacturing, usage, transportation and end-of-life. These last three stages, they found, contributed very little to the product's carbon footprint. For example, running shoes, unlike electronics, require very little energy to use, aside from the energy needed to infrequently wash the shoes.

The bulk of emissions, they found, came from manufacturing. While part of the manufacturing footprint is attributable to a facility's energy source, other emissions came from processes such as foaming and injection molding of parts of a sneaker's sole, which expend large amounts of energy in the manufacture of small, lightweight parts. As Kirchain explains it, "You have a lot of effort going into the molding of the material, but you're only getting a very small part out of that process."

"What stood out was this manufacturing burden being on par with materials, which we hadn't seen in similar products," Olivetti adds. "Part of that is because it's a synthetic product. If we were looking at a leather shoe, it would be much more materials-driven because of the carbon intensity of leather production."

An improved design

In tallying the carbon emissions from every part of a running shoe's lifecycle, the researchers were also able to spot places where reductions might be made. For example, they observed that manufacturing facilities tend to throw out unused material. Instead, Kirchain and his colleagues suggest recycling these scraps, as well as combining certain parts of the shoe to eliminate cutting and welding steps. Printing certain features onto a shoe, instead of affixing them as separate fabrics, would also streamline the assembly process.

Kirchain and Olivetti view their results as a guide for companies looking to evaluate the impact of similar products.

"When people are trying for streamlined approaches to [lifecycle assessments], often they put emphasis on the materials impact, which makes a lot of sense," Olivetti says. "But we tried to identify a set of characteristics that would point you to making sure you were also looking at the manufacturing side -- when it matters."

TAG:Electronics Petroleum Materials Science Global Warming Air Quality Energy and the Environment

失去席位 阿圭苏阿里怒斥F1车手市场黑暗

失去席位 阿圭苏阿里怒斥F1车手市场黑暗

　　西班牙车手杰米-阿圭苏阿里宣布已失去2013年F1车手席位。阿圭苏阿里在一份个人声明中痛斥F1车手市场中的黑暗，讽刺其变成了一场拍卖会。

　　“我无法相信红牛在2012年做出不再考虑我的难以理解的决定，那是在我最好的F1赛季之后。在我失去2013年F1位置之前，我做出了大量的在赛道外的努力。”

　　“在2012赛季的大部分时间里我都被承诺将会获得一个能够经常拿分的车队的位置，他们是这么告诉我的，我也相信了。因为这个，我错过了参加其他比赛的机会。”

　　“那些给我承诺的人给了我一些必须接受的理由，这个我不能说出来。F1变成了一场竞拍。”

　　阿圭苏阿里本来有机会进入宝马车队参加DTM，但是他的位置最终被另一位从F1出来的德国车手格洛克取代。今年，阿圭苏阿里将继续作为倍耐力的试车手测试F1轮胎。

　　“我的F1生涯在我22岁时就完结了？尽管如此，我坚决不相信。所以我将会继续参与F1，要比任何预备车手跑更多的里程。”

　　“我知道自己有多年轻，我知道我的比赛成绩，我相信我配得上坐进一辆能够获胜的F1赛车。我将战斗到底。”

TAG:阿圭苏阿里

紫百合双星闪耀 佛罗伦萨4比1扫国际米兰

紫百合双星闪耀 佛罗伦萨4比1扫国际米兰

Getty Images


　　意甲历史上，国际米兰与佛罗伦萨共有过149次交锋，蓝黑军团61胜50平38负优势明显。不过在佛罗伦萨客场，国际米兰却以17胜32平25负处于下风。双方最近6次交锋蓝黑军团4胜2平保持不败，本赛季首回合较量国际米兰主场2比1力克紫百合。两队近况不佳，国米近8轮仅胜两场，佛罗伦萨新年后6 轮意甲输掉4场。国米方面米利托缺席，萨穆埃尔、穆丁加伊、齐沃、奥比等伤员缺席，斯帅调整首发，卡萨诺与帕拉西奥搭档锋线，两名新援库兹曼诺维奇、科瓦齐奇均首发出场。


第13分钟，佛罗伦萨帕斯奎尔左路传中，约维蒂奇前点头球摆渡，利亚吉奇距门4米处鱼跃冲顶破门！1-0，佛罗伦萨取得领先，慢镜头显示利亚吉奇似乎有越位嫌疑。



战至第28分钟国米首次攻门，瓜林头球摆渡，库兹曼诺维奇距门22米处右脚凌空抽射，球贴着门楣高出！第33分钟，阿奎拉尼传球，约维蒂奇大禁区弧顶处起右脚转身抽射，球炮弹一般飞入球门右上死角！2-0，佛罗伦萨扩大比分。这是约维蒂奇本赛季第10个意甲进球。



第55分钟，阿奎拉尼禁区前沿转身妙传，约维蒂奇突入禁区单挑门将，黑山前锋距门10米处右脚低射，球窜入球门左下死角。3-0，佛罗伦萨锁定胜局。第65分钟，博尔哈-瓦雷罗传球，利亚吉奇左路内切后距门19米处右脚劲射，球进！4-0，佛罗伦萨扩大比分。



第87分钟，阿尔瓦雷斯大禁区弧顶的远射被后卫封挡，卡萨诺距门22米处右脚大力抽出低平弧线，球窜入球门左下死角。1-4，国米打入面子球。


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

技巧赛卫冕冠军帕克出局 五投不中太尴尬

技巧赛卫冕冠军帕克出局 五投不中太尴尬

　　北京时间2月17日，2012-2013赛季NBA全明星周末进入第二天，技巧赛是本日第二个进行的项目，来自圣安东尼奥马刺队的托尼-帕克以卫冕冠军身份出现在这项赛事中，去年的奥兰多全明星赛，帕克首轮耗费29.2秒领跑，冠军轮耗费32.8秒，仍力压朗多和德隆获得冠军。

　　加上今年，帕克已经是第四次参加全明星技巧赛，2009年帕克首轮耗费50.8秒排名倒数第一被淘汰，那一年获得最终冠军的是来自芝加哥公牛队的德里克-罗斯。帕克第一次参赛更是10年前的事情，2003年仅有20岁的帕克首次参加技巧赛，首轮花费45.5秒排名倒数第一，那一年获得冠军的是正值巅峰期的杰森-基德。

　　作为技巧赛的老牌参赛者，帕克是西部队压轴出场，开局不紧不慢的上篮、运球都很顺利，两次传球也只浪费了一次机会，可惜在投篮过程中，帕克连续出手不中，弧顶五次投篮不中连球都投完了，工作人员示意：没球了，继续走吧。最终，帕克只能接受西部垫底的命运，他的成绩是48.7秒，仅好于东部那位连最后上篮都不中的杰夫-蒂格，自然也没能进入决赛轮。

　　本赛季开始至今，帕克场均能够攻下20.8分7.6次助攻，场均得分创职业生涯新高，助攻也是生涯第二，排名联盟第六位，其助攻失误比高达3.04:1，是所有6名技巧赛参赛者中最高的，在邓肯、吉诺比利频繁因伤缺阵的情况下，帕克率领马刺队打出42胜12负的联盟最佳战绩，全明星赛开始前甚至有媒体表示，帕克才是勒布朗和杜兰特之外，本赛季MVP的最有力争夺者。

　　完成技巧赛后，帕克也是一脸自嘲的回到场边，现场还放着卫冕冠军本赛季的精彩镜头回放，好在全明星只是娱乐，帕克要做的，也是在全明星结束之后，带着马刺队保住联盟第一继续前进。


TAG:NBA全明星

巴神补时点球绝杀 米兰2比1积分追平国米

巴神补时点球绝杀 米兰2比1积分追平国米

getty


北京时间2月4日凌晨3点45分，AC米兰坐镇主场迎战意甲联赛第23轮的对手乌迪内斯。上半场沙拉维助攻首秀的巴洛特利攻入了处子球，下半场乌迪内斯由平齐将比分扳平，伤停补时阶段沙拉维制造点球，巴洛特利罚进绝杀点球；最终米兰主场2-1战胜乌迪内斯，继续保持新年联赛不败。



本场比赛是两支球队第76次意甲交锋，在此前75次对阵中米兰取得了33胜30平12负的成绩；米兰在圣西罗对阵乌迪内斯的37场比赛里，20胜13平仅4负占据绝对优势；本赛季两支球队联赛首次交锋时，米兰客场1-2不敌乌迪内斯。今天，阿梅利亚替代阿比亚蒂镇守球门，诺切里诺出战；阿莱格里原定派出的锋线三叉戟是沙拉维、帕齐尼和尼昂，但由于帕齐尼在赛前热身中受伤，巴洛特利顶替其首发，上演米兰处子秀。

上半场

比赛刚一开始，巴洛特利第一次触球就远射尝试攻门，稍稍偏出；第11分钟，尼昂接巴洛特利传球后射门，被帕德利扑出；第15分钟，蒙托利沃防守时铲倒了对手，被主裁判黄牌警告，下轮他将因累计黄牌而停赛；第25分钟，沙拉维左路突入禁区后传中，巴洛特利左脚凌空抽射破门，米兰1-0领先，这是他处子秀的处子球；第27分钟，巴洛特利突然起脚远射，帕德利侧扑将球挡出底线；第40分钟，沙拉维传中，弗拉米尼前插射门被帕德利扑出。上半场比赛结束时，米兰凭借巴洛特利的进球，暂时1-0领先乌迪内斯。

下半场

第51分钟，帕德利将沙拉维的射门扑出；第55分钟，乌迪内斯中场起球发动快速反击，穆列尔拿球快速突破后横敲中路，平齐推射破门，比分被扳成1-1平；第59分钟，尼昂远射打偏；第67分钟，阿莱格里用博扬换下了诺切里诺；第69分钟，康斯塘特边路传中，巴洛特利射门高出横梁；第79分钟，乌迪内斯换上了米兰旧将默克尔，米兰也作出人员调整，罗比尼奥换下了尼昂。


第85分钟，特劳雷出场换下了弗拉米尼；第86分钟，巴洛特利前场任意球直接攻门被帕德利侧扑挡出底线；伤停补时第1分钟，巴洛特利分球到中路，蒙托利沃远射攻门稍稍偏出；第2分钟，沙拉维带球突入禁区被阿兰绊倒，主裁判判罚点球，从慢镜头回防来看，这个判罚有些争议，巴洛特利主罚点球破门，梅开二度助米兰2-1绝杀乌迪内斯。



本轮过后，AC米兰和国际米兰同积40分，落后积分榜排名第3的拉齐奥仅3分。



AC米兰（433）：1-阿梅利亚/20-阿巴特、17-萨帕塔、25-博内拉、21-康斯坦特/16-弗拉米尼、18-蒙托利沃、8-诺切里诺（67'22-博扬）/19-尼昂（79'7-罗比尼奥）、45-巴洛特利、92-沙拉维



乌迪内斯（4411）：25-帕德利/75-赫塔克斯、5-达尼洛、11-多米齐、34-加布里埃尔-席尔瓦/8-巴斯塔、66-平齐（69'52-默克尔）、3-阿兰、21-拉扎里/24-穆列尔（67'37-佩雷拉）/10-迪纳塔莱


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

德米凯利斯父亲因车祸丧生 元帅将回国奔丧

德米凯利斯父亲因车祸丧生 元帅将回国奔丧

Getty Images


胡安.卡洛斯.德米凯利斯，前阿根廷国家队主力后卫、马拉加球星马丁.德米凯利斯的60岁的父亲，今日因车祸而不幸去世。



经过罗萨里奥和科尔多瓦的一条高速公路时，胡安.卡洛斯驾驶的汽车突然失去控制而导致了一起严重的交通事故，并最终不治身亡。一名路经此处的行人也不行罹难。



得知该噩耗之后，德米凯利斯已经离开了西班牙，回国奔丧。这已经是德米凯利斯的身边人在过去2年时间里，第二次因为交通事故而失去生命了。2011年3月20日，德米凯利斯的密友兼经纪人、前阿根廷球星内斯特.阿德里安.德文森特，也因为遭遇车祸而不幸逝世。(Goal.com)


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

收购费尔计划意外受阻 埃弗顿求西甲球星

收购费尔计划意外受阻 埃弗顿求西甲球星

Getty Images


塞维利亚球星内格雷多收到了来自英超球队埃弗顿和热刺的邀请。而在这场争夺中，埃弗顿占据了上风，并且希望在冬季转会截止前用900万英镑完成交易。



埃弗顿收购荷兰国脚费尔的计划以外破产，由于球员的膝盖存在问题，这笔价值860万英镑的交易被迫中止。



大卫莫耶斯转而将目标转向了内格雷多。热刺方面对于内格雷多也很干兴趣，在本月北伦敦球队已经和西甲俱乐部进行了两次接触。



热刺希望可以通过先租后买的方式引进内格雷多。埃弗顿虽然愿意永久买断球员，但是似乎并不打算满足塞维利亚1500万英镑的要价。



根据Goal.com的线人提供的信息，900万英镑的报价就可以满足塞维利亚的要求，塞维利亚目前急需资金，而球员也渴望前往英超效力。



内格雷多出自皇马青训营，本赛季代表塞维利亚出战19场比赛打进了9球。（Goal.com）


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

英格兰公布热身巴西大名单 名将悉数入围

英格兰公布热身巴西大名单 名将悉数入围

Getty Images


值得一提的是，本赛季英超联赛发挥出色的埃弗顿总共有3人入选霍太公的花名册，与联赛卫冕冠军曼城的人数相当。而年轻门将布特兰也成为了24人大名单中唯一还效力于低级别联赛的球员。

英格兰队球员名单(2月6日 vs 巴西):



门将：布特兰(伯明翰)，哈特 (曼城)



后卫：贾基尔卡、拜恩斯(埃弗顿)、卡希尔、阿什利.科尔(切尔西)、格伦.约翰逊(利物浦)、莱斯科特(曼城)、斯马林(曼联)、沃克(热刺)



中场：卡里克、克莱维利(曼联)、杰拉德(利物浦)、兰帕德(切尔西)、列侬(热刺)、米尔纳(曼城)、奥斯曼(埃弗顿)、沃尔科特、威尔谢尔、张伯伦(阿森纳)



前锋：迪福(热刺)、鲁尼、维尔贝克(曼联)、斯图里奇(利物浦) (Goal.com)


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

佛罗伦萨青睐巴黎中场 西索科重回亚平宁

佛罗伦萨青睐巴黎中场 西索科重回亚平宁

Panoramic


当地时间本周三，意大利佛罗伦萨俱乐部通过官网发布了一条消息，确认球队已经就西索科的租借问题与巴黎圣日耳曼展开了谈判。



紫百合本赛季的目标是要进军前四，获得下赛季欧冠的参赛资格。而为了实现此目标，佛罗伦萨希望能在冬季转会期通过引援进一步加强球队实力。西索科正是他们的目标之一。


现年28岁的西索科2011年夏天从尤文图斯加盟巴黎圣日耳曼。到目前为止，这位防守中场一共代表大巴黎参加过超过30场比赛。但本赛季其一直无法获得稳定的出场时间，这也让其兴起了离开的念头。


佛罗伦萨方面希望能先租借西索科至赛季结束，并在租借合同中添加买断条款。


根据紫百合方面的消息，双方将在周三继续谈判，并期望能迅速达成共识。而巴黎圣日耳曼方面则尚未对此事作出回应。（Goal.com）






文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

西甲综述：科斯塔补时绝杀 瓦伦险胜拉科

西甲综述：科斯塔补时绝杀 瓦伦险胜拉科

Twitter @valenciacf


北京时间1月27日凌晨，12/13赛季西甲联赛第21轮先赛四场。凭借着蒂诺-科斯塔补时阶段的破门，瓦伦西亚3比2绝杀被罚下两人的拉科鲁尼亚。莱万特2比1逆转巴拉多利德，比赛同样在最后时刻分出胜负。

拉科鲁尼亚 2-3 瓦伦西亚



第1分钟皮亚蒂右侧角球传中，霍纳斯小禁区右侧头球破门，0比1。32分钟皮齐任意球传中，里基小禁区附近头球破门，1比1。上半场补时第2分钟，里基右路内切后禁区线上左脚劲射破门梅开二度，2比1。52分钟西尔维奥背后铲倒皮亚蒂领受第二张黄牌，拉科10打11。63分钟贝尔纳特左路突破横传，巴尔德斯小禁区内推射破门，2比2。92分钟瓜尔达多传中，里卡多-科斯塔小禁区内头球破门，2比3。93分钟，阿松桑肘击巴尔德斯被直接红牌罚下。拉科鲁尼亚2连败，瓦伦西亚客场3连胜。



莱万特 2-1 巴拉多利德

第8分钟奥马尔角球传中被巴列斯特罗斯顶出，巴拉哈禁区弧顶左脚凌空抽射破门，0比1。44分钟巴克罗罚进直接任意球，1比1。90分钟马丁斯禁区内突破，鲁卡维纳防守中不慎自摆乌龙，2比1。莱万特结束2连败，巴拉多利德结束2连胜。



塞尔塔 1-1 皇家社会

32分钟阿斯帕斯背身回敲，克隆德利禁区中路右脚破门，1比0。50分钟奥古斯托吃到第二张黄牌被罚下，塞尔塔10打11。58分钟卡斯特罗角球传中，埃鲁斯腾多小禁区线上头球破门，1比1。塞尔塔3轮不胜，皇家社会3轮不败。



萨拉戈萨 0-0 西班牙人

78分钟哈维尔-洛佩斯铲倒蒙塔涅斯吃到第二张黄牌被罚下，西班牙人10打11。82分钟萨普鲁纳对巴埃纳犯规也第二次染黄，萨拉戈萨也剩下10人。萨拉戈萨结束3连败，西班牙人结束2连胜。（网易）




文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

齐沃圆月弯刀坎比救主 国米2比2逼平都灵

齐沃圆月弯刀坎比救主 国米2比2逼平都灵

AFP


北京时间1月28日凌晨，意甲联赛第22轮迎来最后一场，国际米兰坐镇主场迎战都灵。比赛进程一波三折，国米早早领先却一度遭逆转，但最终双方2-2握手言和，齐沃和坎比亚索分别为国米破门。其中齐沃利用任意球得分，这是他2011年1月后两年来首球。国米近6轮1胜3平2负，此役过后积40分依旧排名第四，但与身前的拉齐奥差距缩小到3分，与领头羊尤文的差距仍为9分。



国际米兰上一次在主场负于都灵要追溯到1988年。自那以后国际米兰主场对都灵8胜5平占据绝对优势，本赛季首回合交锋，国米也取得2-0完胜。与周中意大利杯相比，斯特拉马乔尼在中前场调整4人，卡萨诺大腿伤愈复出，与加尔加诺、穆丁加伊、长友佑进入先发，顶替了坎比亚索、奥比、贝纳西、佩雷拉，球队以3412阵型出战。对于刚刚经历了与罗马两场大战的国米而言，回到主场作战，他们最需要做的就是拿下3分，力争重返联赛三甲。

上半场

第5分钟，国米获得禁区外距离球门25码处任意球机会，齐沃操刀主罚，左脚兜出一道美妙弧线，对方门将吉列特扑救不及，皮球钻入网窝，1-0，国米取得领先。国米继续猛烈的攻势，第9分钟，国米前场形成连续攻势，帕拉西奥最后面对吉列特的打门，稍稍偏出。

卡里克将获新合同 弗爵赞其状态处于巅峰

卡里克将获新合同 弗爵赞其状态处于巅峰

Getty


曼联中场卡里克近来表现出色，作为对球员的奖励，曼联准备在赛季结束之后和卡里克签订一份新合同。



卡里克目前和曼联的合同将在2014年到期，弗格森准备将球员的合同在演唱一年，但是这份合同要在本赛季结束之后才会签署。



由于卡里克已经年届31岁，曼联方面在续约时保持了很谨慎的态度，根据球员每年的表现，来决定是否要进行续约，而每次续约也只会签署一份一年期的合同。目前曼联队中的斯科尔斯和吉格斯都和卡里克的情况类似。



卡里克目前的周薪为8万英镑，在新签署的合同中，曼联中场的薪资将维持在相同的水平。



卡里克的前东家热刺和西汉姆也都对球员的表现密切关注，如果卡里克在老特拉福德失去位置，两家俱乐部将迅速采取行动。



曼联主帅弗格森对于卡里克近来的表现非常满意，老爵爷认为本赛季是卡里克来到曼联之后最出色的一个赛季。



'卡里克对我们非常重要。' 弗格森在接受采访时说道。 '他的表现非常出色。'



'这是他来到曼联之后表现最出色的一个赛季，他已经成为了一个可以掌控中场的球员。'



卡里克在2006年以1860万英镑的价格从热刺转会曼联，在来到曼联之后的6个赛季中卡里克共代表曼联出战超过300场比赛，平均每个赛季出场次数达到40场，这让他成为了曼联一线队不可或缺的球员。



在效力曼联期间，卡里克收获了多项荣誉，共赢得了4次联赛冠军、1次欧冠冠军、1次世俱杯冠军。（Goal.com）


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

伊布轮休巴黎锋芒依旧 3比1挺进法杯16强

伊布轮休巴黎锋芒依旧 3比1挺进法杯16强

Gettyimages


北京时间1月24日凌晨3点55分，法国杯1/16决赛的一场较量在巴黎圣日耳曼以及图卢兹之间打响，凭借加梅罗、帕斯托雷以及拉维齐的进球，半主力出战的巴黎主场3-1轻松取胜，为图卢兹一度扳平比分的是中场球员塔巴努。巴黎圣日耳曼晋级本赛季法国杯的前16名。


这是法甲积分榜头名与第9的较量，联赛前21轮，巴黎12胜6平3负，积42分以净胜球优势力压里昂居首，而图卢兹则是8胜6平7负积30分位列第9位。两队历史交锋55次，巴黎27胜11平17负占优，主场则是27战17胜6平仅4负。两队本赛季的首次联赛交锋发生在第5轮，当时主场作战的巴黎依靠帕斯托雷以及伊布的进球，2-0轻取对手。法国杯的性质类似于英国的足总杯是所有法国球队都可以参与的赛事，直到32/1决赛时法甲俱乐部才会出战，而上一轮，图卢兹1-0小胜法丙球队布伦，而巴黎则4-3险胜第五级别球队阿拉斯。


相对于上周末客场力克波尔多的比赛，巴黎本场替补尽出，仅马克斯维尔、萨科、维拉蒂、马图伊迪以及拉维齐5人是联赛首发，西里古、雅莱、小卢卡斯以及梅内出任替补，而卡马拉以及伊布干脆没有报名。

上半场

第8分钟，主场作战的巴黎首开纪录，维拉蒂中路策应传球，拉维齐右翼突破低平球传中送到远门柱，及时跟进的快马加梅罗轻松右脚推射破网，1-0。镜头扫过，冬季转会期已经跳槽卡塔尔联赛的巴西前锋内内携妻子在看台上为老东家助威。


第18分钟，客队取得进球，边卫奥里耶右路45度角斜传冲吊送到后点，准备充分的塔巴努力压范德维尔，高高跃起头槌将皮球砸进球门远角，1-1。第37分钟，范德维尔右路精准斜传，前腰帕斯托雷后插上头球攻门，被图卢兹门将布隆德尔出击双拳打出。第39分钟，帕斯托雷左路突破传中，远门柱无人盯防的萨科头球冲顶，可惜皮球被右侧立柱挡出，而加梅罗禁区外的弧线球补射则击中边网。第42分钟，巴黎再失良机，拉维齐策动反击，直塞撕破图卢兹防线，加梅罗反越位面对出击的布隆德尔，左脚挑射空门偏出。

下半场

中场休息时，内内来到球场中央，向巴黎王子公园球场的拥趸们道别，这位巴西老将是上赛季的法甲射手榜头名，但本赛季因为无法与伊布、拉维齐、梅内等名将竞争位置，被出让给卡塔尔联赛球队阿尔加法拉。下半场伊始，安切洛蒂用梅内换下肌肉拉伤的加梅罗。第48分钟，巴黎圣日耳曼利用对方的失误再度取得领先，姆本格边线传球出现失误，被梅内在禁区前沿截得皮球，法国国脚第一时间推传给左路无人盯防的帕斯托雷，后者突入禁区左脚劲射球门左下角得手，2-1。


第65分钟，梅内左路内切送出妙传，拉维齐左脚挑射送入空门，3-1，巴黎锁定胜局，第75分钟，帕斯托雷右路突破图卢兹边卫的防守，送出低平球传中，尚托姆跟进射门，但在对方后卫的干扰下将球打偏。第89分钟，小卢卡斯禁区前沿连续变向戏耍对方球员后，右脚低射偏出左侧立柱。最终，图卢兹未能利用剩余的时间挽回败局，只能接受出局的结果，而巴黎圣日耳曼则昂首挺进本赛季法国杯的16强。


巴黎圣日耳曼（4312）：1-杜歇/2-范德维尔、3-萨科、5-阿尔芒、6-马克斯维尔/4-维拉蒂、7-尚托姆、8-马图伊迪/10-帕斯托雷/11-拉维齐（75' 16-小卢卡斯）、9-加梅罗（46' 17-梅内）


图卢兹（451）：1-布隆德尔/2-姆本格、3-奥里耶（79' 16-雷维埃）、5-雅各、11-宁科夫（60' 15-贾洛）/4-阿克普罗（65' 14-耶德尔）、6-卡普、7-西里埃克斯、8-迪多、10-塔巴努/9-布拉滕




文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

德斯特罗帕拉西奥皆破门 罗马2比1胜国米

德斯特罗帕拉西奥皆破门 罗马2比1胜国米

AFP


北京时间1月24日3:45，在意大利杯半决赛首回合较量中，罗马主场2-1击败国际米兰，这是罗马3天内连续第二次对阵国际米兰。在上半场比赛中，罗马由弗洛伦齐和德斯特罗接连打进两粒头球，帕拉西奥中场休息前为国际米兰扳回一城。两队下半场均无建树。瓜林第16分钟射中罗马右侧立柱。汉达诺维奇第36分钟扑救，皮球击中自家立柱，险些自摆乌龙。罗马右后卫皮里斯上半场送出两次助攻。本赛季三次对阵国际米兰，罗马两胜1平保持不败。双方次回合比赛将移师梅阿查球场进行，这场比赛从1月30日被改期到4月17日。



罗马和国际米兰在历史上总计交手188次。其中，罗马54胜50平84负。在主场同国际米兰的89场比赛中，罗马37胜23平29负。意大利杯自从1922年创立以来，罗马和国际米兰先后5次会师决赛，是意大利足坛会师意大利杯决赛最多的两支球队。目前，两队都碰到了严重的伤停。罗马阵中多多、塔代伊、皮亚尼奇和奥斯瓦尔多4人停赛无缘出战，德罗西受伤。国际米兰方面，卡萨诺、米利托和萨穆埃尔有伤。因为意大利杯半决赛首回合比赛结果不具备决定性作用，泽曼和斯特拉马乔尼都微调了阵容，斯特克伦堡、布尔迪索、贝纳西和奥比等人获得了首发机会。罗马冬歇期新援特罗西迪斯出现在奥林匹克球场看台上。

上半场

第13分钟，弗洛伦齐打破场上僵局。皮里斯右路传中，中路跟进弗洛伦齐头球攻门，皮球钻进死角，1-0。3分钟后，瓜林大禁区右侧获得绝佳起脚机会，皮球击中右侧立柱，弹出底线。1分钟后，罗马右路传中，德斯特罗中路一漏，托蒂点球点附近获得绝佳机会。不过，面对出击的汉达诺维奇，托蒂没有获得起脚机会，只能回做，拉梅拉跟进一脚爆射，皮球被拉诺基亚在门线上挡出。


第32分钟，德斯特罗扩大领先优势。托蒂中路分球，后排插上的皮里斯右路传中，德斯特罗中路跟进头球冲顶，皮球飞进死角，2-0。开场半个小时，皮里斯右路进攻活跃，送出了两脚助攻。第36分钟，托蒂开出左侧角球，国际米兰解围不远，德斯特罗右路拿球之后，让人意外的尝试直接攻门，皮球触地反弹，直接奔向了球门，汉达诺维奇倒地扑了一下，但皮球还是击中立柱弹到门前，瓜林赶紧把球带出危险区域。



第39分钟，帕拉西奥在大禁区前分球，巴尔扎雷蒂尝试背身解围，但没有踢倒皮球，瓜林单刀突入禁区，大力轰门，皮球被斯特克伦堡神勇挡出。第43分钟，帕拉西奥扳回一城。坎比亚索开出前场左侧任意球，罗马后防线造越位失误，帕拉西奥抓住机会杀入禁区，抢在斯特克伦堡前把球打进网窝，2-1。

下半场

斯特拉马乔尼用长友佑都换下了奥比。第48分钟，拉梅拉前场成功抢断齐沃，但最后一传被封堵，布拉德利跟进打门，力量太轻。两分钟后，小胡安中场拼抢拉梅拉成功之后，尝试了一脚远射，皮球打偏。第53分钟，马金奥斯后场解围踢空，帕拉西奥传中，马金奥斯成功铲断。角球开出之后，瓜林大禁区外一脚远射，差之毫厘。



第64分钟，佩雷拉在禁区内背身倒钩解围不远，托蒂大力攻门把球打高。第67分钟，皮里斯解围失误，帕拉西奥抓住机会射门，皮球被挡出之后，又弹到了帕拉西奥脚下，阿根廷人再次射门，皮球被斯特克伦堡拿到。第73分钟，弗洛伦齐送出妙传，德斯特罗右路跟进抡空。第76分钟，阿尔瓦雷斯刚刚出场就有一脚抽射，皮球稍稍偏出。第85分钟，马尔金奥换下托蒂。第89分钟，马尔金奥打出了一脚势大力沉的远射，汉达诺维奇把球封堵。



罗马（433）：24-斯特克伦堡/23-皮里斯、3-马金奥斯（第59分钟，5-卡斯坦）、29-布尔迪索、42-巴尔扎雷蒂/4-布拉德利、77-塔彻西迪斯、48-弗洛伦齐（第76分钟，20-佩罗塔）/8-拉梅拉、22-德斯特罗、10-托蒂（第85分钟，7-马尔金奥）



国际米兰（3511）：1-汉达诺维奇/23-拉诺基亚、26-齐沃、40-小胡安/4-萨内蒂、20-奥比（第46分钟，22-长友佑都）、24-贝纳西（第64分钟，21-加尔加诺）、19-坎比亚索、31-佩雷拉（第74分钟，11-阿尔瓦雷斯）/14瓜林/8-帕拉西奥


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

亨特拉尔曝续约内幕 英超多队曾发来邀请

亨特拉尔曝续约内幕 英超多队曾发来邀请

Getty




沙尔克前锋亨特拉尔承认，自己在今年冬歇期曾收到了来自英超俱乐部的邀请，但是荷兰前锋重申自己从未想过要离开德甲。


据悉阿森纳和利物浦都对荷兰国脚表示了兴趣，但是最终亨特拉尔依然选择了和俱乐部续约两年。


'很多英超球队都向我发出了邀请。但是我从没想过要离开。' 亨特拉尔在接受采访时说道。


'我问过自己是应该留下还是去英格兰。英超是欧洲大路上唯一一个我还没效力过的联赛。'


'对我来说最重要的是我的家庭在这里过得很开心。我们在沙尔克得到了需要的一切。'

29岁的荷兰国脚随后谈论起了自己的未来，亨特拉尔明确表示希望自己在阿贾克斯结束职业生涯。

'阿贾克斯永远是我梦中的俱乐部，在我职业生涯结束之强我想回到那里。但是现在我只想为沙尔克踢好球。'（Goal.com）






文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

特维斯表态正考虑续约 或再留曼城战两年

特维斯表态正考虑续约 或再留曼城战两年

Tevez - Manchester City - Watford


曼城前锋特维斯表示自己正在考虑来自曼城的一份两年新约，但同时也表达了希望重回祖国效力博卡的愿望。


特维斯和曼城的合同将在本赛季结束后到期，根据Goal.com之前独家披露的消息，特维斯希望在履行完在曼城的合同之后回到祖国阿根廷效力自己的老东家博卡青年。


'我和曼城的合同还剩4年了，俱乐部希望再和我续约两年，我正在考虑。' 特维斯在最近接受采访时说道。


'今年的情况和去年不同，我现在并不想结束自己的合同。当他们对我不错的时候我还是很愿意待在这里的。'


'有时我能首发，有时我打不了比赛，这都没关系。'


'当然我永远都渴望回到博卡，尤其是当比安奇担任博卡主帅的时候。' 特维斯说道。


'我希望能够再次穿上那件我热爱的球衣。'


特维斯同时表示自己感觉到已经在国家队渐渐失去了位置，因为现在已经有更出色的球员涌现了出来。


'阿根廷队现在又比我更出色的前锋。' 特维斯说道。 '一个人必须敢于承认这一点，国家队现在已经不需要我了。'



'现在球员水平度比我高出很多。'（Goal.com）




文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

阿根廷辫帅一传一射 国米2比0胜佩斯科拉

阿根廷辫帅一传一射 国米2比0胜佩斯科拉

getty

国米在去年11月击败尤文图斯后，8轮意甲仅仅拿到8分，近3轮更只有1分，在积分榜上滑落至第5。佩斯卡拉近期的状态则比较神勇，近4轮取胜3场。

　　国米原主力中卫拉诺基亚、胡安和萨穆埃尔分别遭遇停赛和伤病，西尔维斯特、坎比亚索和齐沃组成全新三后卫。贝纳西完成国米意甲处子秀。卡萨诺和帕拉西奥搭档双箭头，米利托坐上替补席。


第6分钟，贝纳西策动攻势，瓜林挑传，帕拉西奥依靠速度甩开后卫形成单刀，但他的小角度攻门偏出。第16分钟，贝纳西距门30米外的右脚劲射被后卫一挡后高出。第17分钟，卡萨诺左边路尝试远射，佩林将球扑出。第24分钟，国米间接任意球选择一拨一踩配合，瓜林距门24米处右脚劲射高出。


第31分钟，齐沃中场附近直传，卡萨诺巧妙漏球，帕拉西奥大禁区弧顶转身摆脱特里奇后起右脚低射，1-0!国米取得领先，意甲15场6球，欧联杯3场3球共进9球的帕拉西奥超越米利托成为队内最佳射手。随后佩斯卡拉队塞利克、卡普阿诺两记远射高出。


下半场第54分钟，乔纳森直传，帕拉西奥右路突入禁区后轻巧扣过克鲁奇后横传，瓜林距门6米处推射空门得手，2-0！国米扩大比分。第78分钟，帕拉西奥右路传球，阿尔瓦罗-佩雷拉距门18米处左脚劲射被佩林奋勇扑出。第86分钟，米利托换下帕拉西奥，这是米利托为意大利俱乐部出场的第200场赛事。


　　双方首发阵容：


　　国际米兰（3412）：1-汉达诺维奇/6-西尔维斯特、19-坎比亚索、26-齐沃/42-若纳坦、4-萨内蒂、24-贝纳西、31-佩雷拉/14-瓜林（77分钟，16-穆丁加伊）/99-卡萨诺（70分钟，18-罗基）、9-帕拉西奥（86分钟，22-米利托）


　　佩斯卡拉（4312）：77-佩林/14-巴尔扎诺、88-泰利奇、5-卡普亚诺、11-莫德斯托/20-尼尔森（63分钟，4-卡斯柯内）、18-科卢奇、8-比亚纳森17-/魏斯/80-若纳坦、10-塞利克（76分钟，0-阿莫卡斯托）
（Goal.com）






文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

矿工截胡切尔西猎物 泰森已加盟顿涅茨克

矿工截胡切尔西猎物 泰森已加盟顿涅茨克

shaktar official


顿涅茨克矿工以1500万欧元的价格，正式购入了哈尔科夫球员泰森。双方签署了一份为期5年的合约。

泰森本赛季在俱乐部的出色表现引起了多家欧洲球会的关注，其中包括欧冠未免冠军切尔西。

最终乌克兰豪门赢得了这场争夺，签下了这名24岁的新星。



'在1月10日，顿涅茨克和哈尔科夫就泰森的转会达成了协议。' 顿涅茨克在自己的官方网站发布的声明中说道。



'为此我们支付了1500万欧元的转会费，球员本人非常愿意加盟我们。球员的5年合同将在1月11日开始执行。'



哈尔科夫在2010年将泰森从巴西国际队购入，在代表球队出场的57场联赛中泰森打进13球。



顿涅茨克矿工在本赛季表现出色，以13分的优势高居积分榜首，在新赛季已经进行的18场比赛中赢下了17场。


在欧冠联赛中他们也成功进入淘汰赛阶段比赛，将在1/8比赛中对阵多特蒙德。（Goal.com）


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

纳尼安德森伤愈迎战红军 鲁尼将因伤缺席

纳尼安德森伤愈迎战红军 鲁尼将因伤缺席

Getty


曼联球员纳尼和安德森及时伤愈归队，将可以进入曼联对阵利物浦的比赛阵容，但是鲁尼将因伤错过这场关键比赛。




纳尼的这次伤病已经让他错过了14场曼联的比赛，自从去年11月以来葡萄牙边锋还没有为曼联出场比赛过。巴西中场安德森也是长期伤号，已经缺席了曼联的4场比赛。



鲁尼则因为膝伤将遗憾的错过本场比赛，最早也要等到1月16日的足总杯比赛才能复出。


'纳尼目前已经恢复了训练，安德森也已经随队训练了10天，他们将会入选对阵利物浦的阵容，但鲁尼依然没办法比赛。他今天才刚刚恢复训练。' 弗格森在接受采访时说道。


'他复出的时间也不需要等太久，足总杯对西汉姆的比赛鲁尼将可以出场。'


在周日的比赛之前，弗格森提醒球队集中注意力，不要被对手的情况影响。



'我们只需要关注自己就可以了。' 弗格森继续说道。 '我们尊重每一个对手，苏亚雷斯任何球员都没有区别。'（Goal.com）


文章转载自Goal.com，足球新闻请浏览Goal.com
TAG:

范佩西荣膺英超12月最佳 这是极关键一月

范佩西荣膺英超12月最佳 这是极关键一月

Getty Images




曼联前锋范佩西被评选为英超12月最佳球员。

在12月份，范佩西共代表曼联出战6场比赛，打进5球，帮助曼联在积分榜上保住了对第二名曼城的7分领先优势。



范佩西也以16球的成绩高居射手榜首位，对于赢得英超阅读最佳的奖项，范佩西非常自豪。


'12月对我们来说非常重要。' 范佩西在接受俱乐部官网的采访时说道。

'每个赛季都有几个关键的时间点，而12月份就是其中最重要的一段时间之一。'

范佩西在今年夏天从阿森纳转会来到了曼联，转会费高达2400万英镑，在来到曼联之后，范佩西共为球队出场26次，打进20个进球。（Goal.com）











文章转载自Goal.com，足球新闻请浏览Goal.com
TAG: